Ginger, ginger-avokado-soy, glucosamine sulfate and ginger-ibuprofen in relation to chronic low back pain - a randomised double-blind, placebo-controlled clinical trial with parallel groups for 3 months to illustrate jointhealth.

INTERVENTION: Trade Name: Glucosamin Ferrosan Pharmaceutical Form: Tablet Pharmaceutical form of the placebo: Tablet Route of administration of the placebo: Oral use Trade Name: Ginger‐biocomplex TQ Pharmaceutical Form: Capsule, soft Pharmaceutical form of the placebo: Capsule, soft Route of administration of the placebo: Oral use Trade Name: Ginger/avocado/soy‐biocomplex VF Pharmaceutical Form: Capsule, soft Pharmaceutical form of the placebo: Capsule, soft Route of administration of the placebo: Oral use Trade Name: Ibuprofen NM Pharma 400 mg Pharmaceutical Form: Tablet Pharmaceutical form of the placebo: Tablet Route of administration of the placebo: Oral use CONDITION: Chronic low back pain PRIMARY OUTCOME: Main Objective: To evaluate the clinical efficacy of ginger, ginger/avokado/soy, glucosamine sulphate and gin‐ger/ibuprofen in adults with chronic low back pain Primary end point(s): Pain relief based on VAS (visual analog scale) between inclusion and end‐visit for each of the 4 intervention groups (ginger, ginger/avocado/soy, glucosamine sulphate and ginger/ibuprofen) compared to placebo. Secondary Objective: INCLUSION CRITERIA: Subject is able and willing to give written informed consent. Subject is able to read, comprehend and record information required in the protocol. Chronic low back pain is defined as pain every day or nearly every day for ?3 months up to inclusion. The low back is defined as the area of the back bounded by the lowest rib and the crease of the but‐tocks. The pain should be classified as Quebec Task Force Class I (pain without radiation to an ex‐tremity and without neurologic signs) or Class II (pain with radiation to an extremity but not below the knee and without neurologic signs). Subject is male or female, 30 years or more of age. A fertile female is eligible to participate in the study if she is has a negative pregnancy test at inclusion and agrees to use one of the acceptable methods of contraception during the study. No intake of glucosamine sulphate, ginger or ginger/avocado/soy within the last 3 months. Calming and muscle relaxing m