Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Upper Limb Motor Function in Patients with Cerebral Hemorrhage

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: taVNS Group:A portable transcutaneous nerve stimulation device was adopted, with electrodes placed in the left auricular concha area. The stimulation parameters were set as follows: frequency at 25 Hz, pulse width at 200 µs, and current intensity ranging from 1–5 mA, which was adjusted to the maximum tolerable level for the patient and kept below the pain threshold.;Sham Stimulation Group:An identical device with the same appearance and operation mode as that used in the intervention group was applied, with electrodes placed on the earlobes and the current intensity set at < 0.1 mA.; CONDITION: Upper limb motor dysfunction after intracerebral hemorrhage PRIMARY OUTCOME: Changes in Fugl‐Meyer Assessment of Upper Extremity (FMA‐UE) score; SECONDARY OUTCOME: Brunnstrom Recovery Stages (BRS);Modified Barthel Inde X(MBI);Incidence of adverse events; INCLUSION CRITERIA: 1. Aged between 18 and 75 years old; 2. First‐ever intracerebral hemorrhage confirmed by cranial computed tomography (CT) or magnetic resonance imaging (MRI); 3. Unilateral hemiplegia complicated with upper limb motor dysfunction, with a Fugl‐Meyer Assessment of Upper Extremity (FMA‐UE) score ranging from 20 to 50; 4. Signed informed consent obtained from the patient or their legal representative.
Epistemonikos ID: a3a0c2627a3ffae97248e3916e16ad34fd0ac9d8
First added on: May 09, 2026