The effect of Glycine Betaine on fasting and Post methionine load homocysteine concentrations in healthy volunteers.

INTERVENTION: A 6‐week intervention study investigating the effect of dietary manipulation versus dietary supplementation of glycine betaine on fasting and post‐methionine load homocysteine concentrations. CONDITION: Healthy Volunteers N/A PRIMARY OUTCOME: Homocysteine concentrations SECONDARY OUTCOME: Plasma glycine betaine, choline, methionine, and urine glycine betaine and choline concentrations. INCLUSION CRITERIA: Healthy volunteers with no previous history of vascular disease and no illness requiring medication, normal haemoglobin concentration.