Antibacterial Photodynamic Therapy in the Management of Peri-implantitis

Clinical signs of inflammation in peri‐implantitis include bleeding on probing,suppuration, increased probing depth, and radiographic signs of bone loss. Currently, thebest treatment options for peri‐implantitis include non‐surgical methods of biofilmremoval in the supra‐mucosal area around implants, and comprehensive guidance onself‐performed infection control procedures. With more advanced peri‐implantitis,anti‐infective surgical treatment protocol would be needed.Matrix metalloproteinase 8 (MMP‐8) has been found to be elevated in association with oralinfections, such as periodontitis and peri‐implantitis. The level of active MMP‐8(aMMP‐8) can detect to determine tissue health and to assess inflammation, and can easilybe measured during a regular dental appointment with a chairside test.The Lumoral Treatment is a CE‐marked medical device developed to provide a potent,targeted antibacterial action on dental plaque in a home environment. The methodmechanism of action is antibacterial photodynamic therapy (aPDT). The method is used byswishing a mouth rinse, which has a strong adherence to dental plaque. The plaque‐adheredphotoactive mouth rinse can be activated by a simple‐to‐use light applicator. Preliminaryresults have shown a promising anti‐inflammatory response in addition to plaquereduction.