Abdominal Midline Wound Closure: Small Tissue Bites Versus Large Tissue Bites

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This clinical trial is designed to evaluate two different methods of closing abdominalwounds after midline laparotomy surgery in adults. A midline laparotomy is a commonsurgical procedure in which an incision is made along the middle of the abdomen to allowsurgeons access to internal organs. Proper closure of this incision is important becausecomplications such as infection or reopening of the wound can lead to pain, delayedrecovery, longer hospital stays, and additional treatment.The study focuses on comparing a "small stitch" technique with the more traditional"large bite" technique used to close the abdominal wall at the end of surgery.Researchers want to determine whether the small stitch method can improve healing andreduce complications after surgery.In the small stitch technique, sutures are placed approximately 5 millimeters from theedge of the wound and spaced 5 millimeters apart. This approach is designed to distributetension more evenly across the wound and may help preserve blood supply to the tissues,potentially improving healing. In the large bite technique, stitches are placed fartherfrom the wound edge and farther apart, which is the conventional method commonly used inmany surgical settings.The main goals of the study are to determine:Whether the small stitch technique reduces the risk of surgical site infections Whetherthe small stitch technique lowers the chance of wound dehiscence, a serious complicationin which the surgical wound partially or completely reopens after surgery Adultsundergoing midline laparotomy surgery may be eligible to participate. During theprocedure, participants will have their abdominal incision closed using either the smallstitch or the large bite technique. The method used will be assigned according to thestudy protocol so that researchers can fairly compare outcomes between the two groups.After surgery, participants will continue with routine postoperative care and attendfollow‐up visits approximately 2 weeks and 1 month after their operation. At thesevisits, the surgical wound will be examined for signs of infection, delayed healing,wound reopening, pain, or other complications. Researchers will collect and compare theresults from both groups to determine which closure method provides better outcomes.The information gained from this study may help surgeons identify the safest and mosteffective way to close abdominal incisions, potentially improving recovery and reducingpostoperative complications for future patients undergoing abdominal surgery.
Epistemonikos ID: a2860dabc9e784db19597fd5c02b61db1dbc220c
First added on: Jun 02, 2026