Evaluation of the effect of misoprostol on cesarean bleeding

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: Intervention 1: First intervention group: After umbilical cord clamping during surgery, the patient will receive 20 oxytocin units within half a liter of Ringer's serum at a rate of 15 cc per minute.In the first intervention group, we place 200 micrograms of misoprostol in the patient's sublingual (It should be noted that Mizoprostol 100 mg tablets are from Abu Reihan Company and 10 units of Oxytocin ampoules are from Alborz Daroo Company). If proper uterine contraction does not occur after a few minutes (maximum 5 minutes), if the initial intervention is not enough, oxytocin will be repeated up to 100 units (inside the Ringer's serum) and if we need more medication, misoprostol. We continue up to 1000 micrograms. Intervention 2: Second intervention group: After umbilical cord clamping during surgery, the patient will receive 20 oxytocin units within half a liter of Ringer's serum at a rate of 15 cc per minute.In the second intervention group, we place 200 micrograms of misoprostol in the patient's rectal area (It should be noted that Mizoprostol 100 mg tablets are from Abu Reihan Company and 10 units of Oxytocin ampoules are from Alborz Daroo Company). If proper uterine contraction does not occur after a few minutes (maximum 5 minutes), if the initial intervention is not enough, oxytocin will be repeated up to 100 units (inside the Ringer's serum) and if we need more medication, misoprostol. We continue up to 1000 micrograms. Intervention 3: Control group: After umbilical cord clamping during surgery, the patient will receive 20 oxytocin units within half a liter of Ringer's serum at a rate of 15 cc per minute(It should be noted that the oxytocin ampoule is 10 units from Alborz Daroo Co.) . If proper uterine contraction does not occur after a few minutes (maxim CONDITION: The amount of bleeding from a cesarean section. PRIMARY OUTCOME: Bleeding during cesarean section. Timepoint: Bleeding is removed during surgery and after surgery. Method of measurement: The amount of blood lost in each group at the end of the operation, based on the amount of blood in the suction and the estimated blood volume absorbed by each gauze and long gauze with the scales before and after The operation is weighed and the amount of clot excreted from the vagina after uterine massage is calculated at the end of the operation and will be recorded in the desired checklist. INCLUSION CRITERIA: Patients between the ages of 18 and 40 Candidates for cesarean section Gestational age between 37 and 40 weeks Candidates for Spinal anesthesia Written consent from the patient Single pregnancy Low transverse uterine incision
Epistemonikos ID: a25b072344718c72cce187e05a6755735cdc4f5b
First added on: Apr 22, 2021