Effect of Probiotics Consumed During Pregnancy on the Incidence of Mastitis

The requested reference [b36aa6b67cfa58ea371dff217cbcd6291b1bd394] no longer exists in our database. It has been replaced by the current reference: [fdb7cb983959af102d3e581b85199ac60ae649dd]

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2019
Pregnancy and lactation are important moments for the child that will determine their development and future health. One of the key processes is when the microbiota is established in the baby. Contamination during delivery with the mother's vaginal flora, as well as bacteria from the microbiota of breast milk, are important sources for intestinal colonization. However, the mother's microbiota can suffer alterations that affect the health of the mother and can also have an effect on the baby. Mastitis is a condition of the mammary gland that can affect between 3‐30% of women during the period of lactation and is the first cause of abandonment of it. It is associated with a dysbiosis with the proliferation of microorganisms in milk such as Staphylococcus and Streptococcus. Previous studies carried out with the strain L. fermentum CECT5716 have demonstrated a powerful regulating activity of the microbiota of breast milk that translates into a preventive and curative effect on mastitis. The highest incidence of mastitis occurs during the first weeks after delivery, so the investigator's working hypothesis is that the modulation of the maternal microbiota before delivery would improve the effectiveness of the probiotic strain consumption.
Epistemonikos ID: a227edcee5c44100b24aef28aba22e570ccbde8c
First added on: May 22, 2024