Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma

Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2017
Preclinical models show that a daily antiangiogenic regimen at low-dose may be effective against chemotherapy-resistant tumors. The aim of this study is to evaluate the efficacy of maintenance therapy with continuous oral cyclophosphamide and methotrexate in patients with high grade, operable, metastatic osteosarcoma (OST) of the extremities. The primary end point is event-free survival (EFS) from randomization
Epistemonikos ID: 9dae32a683b54174eef229f3dd41e274751fe529
First added on: Dec 20, 2022