Assessment of Efficacies of Cardiac Resynchronization Therapies (CRT-P/D) for Heart Failure Patients in China (ADOPT Trial) rationale, design and end-points

INTERVENTION: A:Therapy with CRT;B:Therapy without CRT; CONDITION: heart failure PRIMARY OUTCOME: The composite of all‐cause mortality; SECONDARY OUTCOME: unplanned hospitalisation by cardiovascular reason;Days alive and not in hospital for unplanned cardiovascular cause during the minimum period of follow‐up; INCLUSION CRITERIA: Heart failure patients who must meet all criteria: (1) ischemic or nonischemic cardiomyopathy; (2) NYHA classes III‐IV despite OPT; (3) normal sinus rhythm; (4) LVEF<=35%; (5) LV end‐diastolic diameter >=55 mm; (6) and wide QRS complex>=120 ms.