A Non-Inferiority Study of Liposomal Bupivacaine Combined with Bupivacaine versus Bupivacaine Alone for Postoperative Analgesia in Arthroscopic Knee Meniscus Surgery

INTERVENTION: Group LB:Adductor canal block with liposomal bupivacaine combined with bupivacaine.;Group B:Bupivacaine adductor canal block; CONDITION: Meniscus injury PRIMARY OUTCOME: NRS scores for resting pain immediately upon emergence and at 6, 12, 24, and 48 h postoperatively.; SECONDARY OUTCOME: Demographic and clinical characteristics;Athens Insomnia Scale (AIS) scores at postoperative day 1, the number of patients with an AIS score = 6 at postoperative day 1, and the Pittsburgh Sleep Quality Inde X(PSQI) at preoperative day 1.;Lower extremity motor function;Intraoperative fluid volume.;The number and proportion of patients with a resting NRS pain score > 3 within 48 h postoperatively.;Time to first pain.;Complications;Postoperative rescue analgesic use.;Time to first PCA pump press;Incidence of intraoperative adverse cardiovascular events.;Intraoperative supplemental sufentanil dose.;Movement‐evoked pain immediately upon emergence and at 6, 12, 24, and 48 h postoperatively.;Quality of recovery at 48 h postoperatively;Surgical duration;Patient satisfaction with postoperative analgesia;Hospital Anxiety and Depression Scale (HADS) scores at 1 day preoperatively and 1 day postoperatively.;Area under the NRS pain score–time curve (AUC) for movement‐evoked pain within 48 h postoperatively.;Area under the NRS score–time curve (AUC) for resting pain within 48 h postoperatively.; INCLUSION CRITERIA: 1.Patients aged 18–65 years with ASA physical status I or II scheduled to undergo arthroscopic partial meniscectomy or meniscal repair of the knee.