Efficacy of Herbal enema prescriptionII(DHEP II) in the treatment of mild or moderate active symptoms of ulcerative colitis: a multicenter prospective randomized control clinical trial

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2019
INTERVENTION: Experimental group:Mesalazine+DHEP II;control group:Mesalazine+Compound Huangbai lotion; CONDITION: Ulcerative colitis PRIMARY OUTCOME: relapse Intervals; SECONDARY OUTCOME: Comprehensive efficacy criteria;TCM symptom evaluation criteria;Truelove‐Witts;Mayo index;Evaluation criteria for mucosal lesions;Safety evaluation standard;ESR;CRP;albumin;HB;IL6;TNF‐a;Calprotectin;Intestinal flora; INCLUSION CRITERIA: (1) Patients meeting the Western diagnostic criteria for ulcerative colitis(See the research proposal for details); (2) Comply with the diagnostic criteria for TCM syndromes of ulcerative colitis(See the research proposal for details); (3) The condition is mild to moderate active patients aged 18‐75 years; (4) No history of diarrheal disease or other gastrointestinal diseases in the past 4 weeks; (5) Antibiotics and microecological preparations were not taken within the past 1 month; (6) Signed into the study informed consent form.
Epistemonikos ID: 9bdef9610a83b778ca6f7875bf0fc9e17aff2b4d
First added on: Mar 23, 2022