A Randomized Double-Blind Placebo-Controlled Evaluation of the Safety and Efficacy of Wild Sage Metabolites in Preventing Snoring, Improving Sleep, and Activating Alpha Wave Brain Frequencies in Healthy Adults

Upper airway problems and stress can cause sleep disorders. The present study was designed to evaluate the efficacy and safety of wild sage metabolites (WSM) for snoring treatment and alpha wave activation in healthy men and women. A total of 42 subjects compliant with inclusion criteria were randomly assigned to one of the two groups, viz. Group 1-WSM and Group 2-Placebo, using a simple randomization process. Consumption of WSM by healthy men and women resulted in decrease of Pittsburgh Sleep Quality Index (PSQI) global score by 29%, improved assessment by their sleep mates, and increased alpha brain wave by 55%. In conclusion, medication with WSM resulted in significant reduced snoring, stress, and improved sleep quality after 30 days, with a good tolerance among subjects. No side effects or adverse events were reported during the study. Hence, WSM at 450 mg/day could be recommended as an effective agent for snoring treatment, improving sleep quality, and stress reduction.