Early Diabetes Intervention Trial

INTERVENTION: Subjects valid for inclusion were randomly assigned to acarbose 50 mg tds, metformin 500 mg tds, a combination of the two, or matching placebo. CONDITION: Impaired glucose tolerance ; Nutritional, Metabolic, Endocrine ; Diabetes PRIMARY OUTCOME: Not provided at time of registration SECONDARY OUTCOME: Not provided at time of registration INCLUSION CRITERIA: Subjects aged 30 to 70 years inclusive, with fasting hyperglycaemia; defined as a fasting plasma glucose (FPG) level =5.5 mmol/l and <7.8 mmol/l on two occasions at least 1 week apart