Effect of the WAIO Digital Platform on Multidimensional Wellbeing in Adults in Argentina

This study uses a sequential mixed‐method design consisting of an instrumentalcalibration phase followed by a two‐arm, parallel randomized controlled trial.During the initial instrumental phase, the preliminary 40‐item WAIO Integral WellbeingInventory, culturally adapted from the SAMHSA eight‐dimension wellness framework, willundergo psychometric evaluation. The first approximately 200 participants completing thebaseline assessment will contribute to this phase. The planned evaluation includesassessment of internal consistency, factorial structure, convergent validity,comprehensibility, and test‐retest reliability. Items retained after this prespecifiedcalibration process will be used for subsequent longitudinal assessments.The experimental phase will evaluate a digital wellbeing intervention delivered throughthe Wellbeing All‐In‐One (WAIO) progressive web application. WAIO integrates more than 30interconnected digital tools organized around eight dimensions of wellbeing: physical,emotional, social, occupational, spiritual, financial, intellectual, and environmental.Artificial intelligence is used to personalize aspects of the user experience.A total recruitment target of 2,000 adults in Argentina is planned. Participants enteringthe randomized phase will be allocated to one of two parallel groups. Participants in theimmediate‐intervention group will receive access to WAIO and weekly engagement messages.Participants in the active waitlist control group will receive general health informationmonthly and will not receive access to WAIO during the six‐month comparison period.Access to WAIO will be provided to the waitlist group after completion of that period.Participants will be assessed at baseline and followed longitudinally over six months.The study is designed to evaluate the trajectory of multidimensional wellbeing, therelationship between exposure to the digital intervention and changes in wellbeing,participant retention, and intervention safety.The study includes prespecified safety procedures for the identification and managementof potentially serious risk signals detected during use of the digital platform.