The effects of exercise intensity on immune function and glucose regulation

INTERVENTION: 6 bouts of high‐intensity intermittent exercise @ 100% VO2max, on a stationary cycle ergometer with a work‐to‐rest ratio of 1:4 over a period of 30‐minutes. Active recovery consists of cycling @ 50% VO2max and performance will be monitored on the software associated with the cycle ergometer. A minimum wash‐out period of three days will take place between trials. CONDITION: Overweight/obesity Prevention of type 2 diabetes/prediabetes PRIMARY OUTCOME: Glucose control via an oral glucose tolerance test and continuous glucose monitor SECONDARY OUTCOME: Inflammatory markers; pro‐ and anti‐inflammatory markers such as IL‐6, CRP and IL‐10. INCLUSION CRITERIA: BMI > 25 Sedentary