Efficacy study of olanzapine combined with MECT on the treatment of refractory schizophrenia

Authors
Category Primary study
JournalChinese Journal of Clinical Rational Drug Use
Year 2013
OBJECTIVE: To observe the Tsavo olanzapine combined with modified electroconvulsive therapy refractory schizophrenia patients. METHODS: in our hospital in January 2011 - December 2012 admitted 72 patients with refractory schizophrenia were randomly divided into control and experimental groups, each group of 36 cases. Control group were receiving olanzapine; improved experimental group received electric shock treatment on this basis. Comparison of the two groups of treatment. RESULTS: were cured in 9 cases, 12 cases markedly improved in 12 cases, 4 cases; the control group healed in 3 cases, 8 cases were markedly improved in 11 cases, 12 cases, two groups the difference was statistically significant (P0.05 ). Symptoms of adverse reactions in the experimental group salivation, lethargy, sinus tachycardia, and constipation were significantly lower than the control group, the difference was statistically significant (P0.05). CONCLUSION: olanzapine combined modified electroconvulsive therapy refractory schizophrenia, with a more satisfactory clinical efficacy, high clinical value.
Epistemonikos ID: 95c5c14db419c08255561705d77af2ce09e2ef4e
First added on: May 04, 2016