The Combined Use of PRP With Lipoaspirate and/or Bone Marrow Aspirate in Osteoarthritis

The purpose of this study is to demonstrate the efficacy of the combined use of platelet‐rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP plus lipoaspirate, PRP plus bone marrow aspirate, and PRP plus both lipoaspirate and bone marrow aspirate. A total of 255 participants will be randomly assigned to one of three treatment groups: Group A will receive PRP plus lipoaspirate, Group B will receive PRP plus bone marrow aspirate, and Group C will receive tri‐partite therapy of PRP + lipoaspirate + bone marrow aspirate which allows for 85 in each group. The combination of biologic materials will be injected in to an arthritic joint.