Is perfluorocarbon and air more effective than perfluorocarbon or air alone when removing emulsified silicone oil following treatment for a detached retina?

INTERVENTION: The study should include at least 10 to 20 patients from each center with any period of silicone tamponade after rhegmatogenous retinal detachment repair that are considered for silicone oil removal. The participants are randomized into two groups. In both groups the intraocular fluid (IOF) should be obtained before and after washing the vitreous cavity by 25G aspiration cannula and simultaneous tamponade with air. The surgical approach is based on 25‐gauge pars plana silicone oil removal. Irrigation of balanced salt solution is supplied under the pressure of 20‐30 mm Hg (in the range). The retrobulbar block is done for akinesia and anesthesia supply. After three transconjunctival port incisions are made, the continuous infusion is installed in the inferior temporal segment approximately 3.5 mm away from the limbus. The main portion of SiO (silicone oil) is extracted through the side port by active aspiration. An extrusion cannula is injected in the mid‐posterior vitreous cavity with the assistance of an endoilluminator. For the fluid/ air exchange, simultaneously 4 ml intraocular fluid with the remaining emulsified silicone oil (ESiO) is aspirated with a 5‐ml syringe with an endovitreal long‐tipped cannula. This is the sample used for investigation. The aspirated intraocular fluid is immediately poured into two wells of a sterile plastic 24‐well culture plate with an inverted marking of 5 areas on the inside surface of the bottom. Air/fluid exchange is than applied with simultaneous continuous irrigation of balanced salt solution under increased pressure (30‐40 mm Hg) with continuous air aspiration with gradual and partial elevation of the extrusion cannula on the very surface of the intraocular liquid in the direction to anterior chamber. During this procedure, the irrigation port is turned away from the macular region and optic nerve. This step is important to exclude the traumatic influence of the infusion to the retina and to CONDITION: Removal of silicone oil following treatment of vitreoretinal disorders. ; Eye Diseases PRIMARY OUTCOME: Quantitative analysis of silicon using an Image J program and an automated computerized program that is currently under development SECONDARY OUTCOME: ; 1. Visual acuity assessed using a Snellen chart on day 1 and after one month.; 2. Intraocular pressure measured using pneumotonometry on day 1 and after one month.; INCLUSION CRITERIA: 1. Retinal detachment surgery with silicone oil tamponade with silicone oil emulsification 2. Aged 20‐90 years