Double-blind, randomized trial of piroxicam and codeine in cancer pain.

Evaluates the acute analgesic potency and tolerance of a single oral dose of piroxicam, codeine, and a combination of both drugs in a sample of 88 patients (aged 18–80 yrs) with chronic pain due to cancer. Assessments of pain intensity and relief were made by a nurse in 6 hourly increments after dosing. After 6 hrs, patient and nurse both gave a global impression of therapy. Volunteered side effects and their severity were noted. No significant differences distinguished the 3 treatment groups for pain intensity, analgesic efficacy, speed of action, or side effects. Results suggest that piroxicam may be of use in treating certain types of cancer pain. (PsycInfo Database Record (c) 2021 APA, all rights reserved)