The effect of fennel extract on antimullerian hormone and ultrasound criteria in infertile women with Occult premature ovarian failure

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2023
INTERVENTION: Intervention 1: Intervention group: 30 mg fennel capsules manufactured by Barnage Essential Oil Company will be used. One capsule will be consumed daily for 2 months. Intervention 2: Control group: Placebo capsules that are similar in appearance (shape, size, color, etc.) to fennel capsules produced by Barch Essential Oil Company and will be consumed daily by Badmet participants for 3 months. CONDITION: Occult premature ovarian insufficiency. PRIMARY OUTCOME: Comparison of AMH levels in the group receiving fennel capsules and the control group. Timepoint: At the beginning of the study (before the start of the intervention) 2 months after the start of the intervention. Method of measurement: AMH laboratory kit. Comparison of the number of ovarian antral follicles in the group receiving fennel capsules and the control group. Timepoint: At the beginning of the study (before the start of the intervention) 2 months after the start of the intervention. Method of measurement: Real time transvaginal ultrasound with Madison v20 brand, which is made in South Korea. INCLUSION CRITERIA: 1) Evidence suggesting occult premature ovarian failure: antimullerian hormone > 1, or reduction of ovarian follicular reserve by transvaginal ultrasound (reduction of antral follicles less than 6 in each ovary) 2) Presence of menstrual cycles 3) Age 20‐40 years 4) Having Both ovaries 5) No other causes of female infertility including fallopian tube disorders, endocrine system disorders and uterine disorders, endometriosis, hyperprolactinemia and sexual disorders based on the patient's medical record. 6) Not using complementary herbal medicines in the last three months
Epistemonikos ID: 9448ce4b6d3c4f723196d191e91c9abe8fb7ea5b
First added on: Feb 20, 2024