Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2016
Preclinical studies have demonstrated in mouse models that (PYR1)-apelin-13 exerts a glucose-regulating action in vivo. The (PYR1)-apelin-13 effect on insulin sensitivity in healthy overweighed volunteers has been previously assessed in a phase I clinical trial (APELINS study; NCT02033473). The APELINS-2 clinical trial aims to expand the initial proof of concept to the population targeted by future innovative insulin-sensitizing therapies: patients living with type 2 diabetes.
Epistemonikos ID: 93e4fd8bf7dff1647a54cb3b998b9b6ba815208a
First added on: May 12, 2024