Authors
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Pan, W., Ek, M., Fenwick, E., Hu, Z., Jiang, Y., Tan, H., Chen, Z., Hoang, Q., Saw, S.-M., Lamoureux, E., Lan, W., Yang, Z. -More
Category
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Primary study
Pre-print»medRxiv
Year
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2025
PurposeA psychometric evaluation of the Chinese Impact of Vision Impairment (C-IVI) questionnaire in an adult cohort with high myopia using Rasch Analysis and determination of the relationship between vision-related quality-of-life (VRQoL) and myopia macular degeneration (MMD).
MethodsWe used the baseline visit data of the AIER-Singapore Eye Research Institute (SERI) High Myopia Adult Cohort Study. VRQoL was assessed using the 28-item C-IVI. Rasch analysis was conducted to evaluate the overall C-IVI and domain scores ( Mobility and independence--MB, Reading and accessing information--RD, and Emotional well-being-- EWB), including response category functioning, precision, unidimensionality, targeting, and differential item functioning (DIF). The criterion validity, C-IVIs ability to distinguish participants based on severity of vision impairment (VI), spherical equivalent, and the presence of MMD were analyzed using ANOVA and pairwise t-tests.
ResultsThere were 431 participants, with mean (SD) age of 42.2 (7.1) years, spherical equivalent of -8.3 (3.8) D, and visual acuity of 0.1 (0.2) LogMAR. Of these, 15.8% presented MMD, 79.4%, 13.5%, 7.0%, and 0.2% had no, mild, moderate, and severe VI, respectively. Response thresholds were ordered for the overall and three domains. The overall range-based precision was 0.94, and 0.80 for each domain. The three domains demonstrated unidimensionality. DIF was uniform in overall and EWB, but not the MB and RD domains. Person estimates decreased with increasing VI severity, worsening SER, and presenting MMD (all p<0.05) for the overall and domain scores.
ConclusionsThe C-IVI questionnaire is a valid and reliable tool for assessing VRQoL in adults with high myopia in China.
The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license
Epistemonikos ID: 92fc35684f1a85df77f5f783fbe1c95091af6622
First added on: Jun 23, 2025