Effect of music on pain in preterm neonates undergoing the arterial puncture

Every day preterm infants are submitted to arterial puncture in the first hours of life for testingthe gases and pH dosage. Although arterial puncture is painful, it is rarely accompanied byany analgesic measure. The study Aimed to evaluate the effects of interventions: music, musicand 25% glucose, and 25% glucose in relieving the pain of preterm infants undergoing arterialpuncture, and analyze the association of neonatal and therapeutic variables with the painscores of obtained through the Premature Infant Pain Profile (PIPP). A cross-sectionalrandomized clinical trial of triple-blind experimental type, carried out at the Neonatal CareUnit (NCU) in a public hospital in Fortaleza-CE, Brazil, from November 2011 to August2012. The sample consisted of 80 preterm infants, 24 randomized in Experimental Group 1(EG1–music); 33 in Experimental Group 2 (EG2–music and 25% glucose); and 23 inPositive Control Group (PCG). Lullaby music was played for 10 minutes before arterialpuncture through a MP3-playerconnected to earphones, for the infants in the EG1 e EG2,with 25% glucose administered to infants in the EG2 and PCG two minutes before arterialpuncture. The primary outcome was the pain scores obtained with the PIPP in the first 240seconds after the arterial puncture in an interval of 30 to 30 seconds. Secondary outcomeswere the changes related to facial movements, Heart Rate (HR) and oxygen saturation (SpO2).This research was approved by the ethics committee under protocol No. 060 717/11. It wasobserved that the numeric neonatal variables of the preterm infants in the EG1 versus totalPIPP scores presented significantpin the variables: head circumference (HC–p=0.003),chest girth (CG–p=0.032)...