金花清感颗粒治疗新型冠状病毒感染肺炎的临床观察 段璨; 夏文广; 郑婵娟; 孙国兵; 李正良; 李庆琳; 李平; 张荷玲; 杨丰文; 张伯礼; 刘清泉.中医杂志 /Clinical Observation of Jinhua Qinggan Granule in Treating Pneumonia Infected by Novel Coronavirus

OBJETIVE: To observe the novel coronavirus Qinggan Granule in treating pneumonia caused by new coronavirus infection. Methods one hundred and twenty-three patients with covid-19 were randomly divided into treatment group (treated with Jinhua Qinggan Granules Combined with conventional treatment) and control group (treated with conventional treatment only), with 82 cases in the treatment group and 41 cases in the control group, The clinical symptom disappearance rate, TCM Syndrome Scale score, hospitalization rate, Hamilton Anxiety Scale score, outpatient satisfaction score and incidence of adverse reactions were observed before and after treatment for 5 days. RESULTS: there was no significant difference in baseline data between the two groups. The disappearance rates of clinical symptoms in treatment group and control group were as follows fever 80.3% and 53.1%, cachexia 80.8% and 81.3%, headache and body pain 77.8% and 66.7%, head and body weight 75.0% and 88.9%, fatigue 77.6% and 53.8%, cough 66.1% and 42.9%, expectoration 85.3% and 46.2%, sore throat 77.8% and 60.0%, pharyngitis 85.7% and 75.0%, dry throat 83.3% and 100.0%, nasal congestion and runny nose 87.5% and 66.7%, nausea and vomiting 83.3% and 71.4%. The hospitalization rate was 10.98% and 24.39% respectively, and the incidence of adverse reactions was 32.93% and 0. The disappearance rate of clinical fever, cough, fatigue, expectoration symptoms, TCM Syndrome Scale score and Hamilton Anxiety Scale score in the treatment group were significantly lower than those in the control group (P < 0.05 or P < 0.01), There was no significant difference in the hospitalization rate, the disappearance rate of chills, head and body pain, head and body weight, sore throat, itchy throat, dry throat, nasal congestion, runny nose, nausea and vomiting, and outpatient satisfaction score between the treatment group and the control group (P > 0.05), but the hospitalization rate was lower than that of the control group, The disappearance rate of head and body pain, sore throat, itchy throat, stuffy nose and runny nose, nausea and vomiting were higher than those in the control group. The disappearance rate of symptoms was higher in both groups. The novel coronavirus granule can significantly reduce the fever, cough, fatigue and expectoration of the new coronavirus pneumonia patients and relieve their psychological anxiety.