Assessment of Different Medications in Modifying the Efficacy of Anesthesia in Mandibular Molars With Acute Irreversible Pulpitis

The goal of this clinical trial is to assess the effect of preoperative * Oral Tablets of Trypsin/Chymotrypsin/Bromelain Limitless Allzyme® (15 microkatal/42microkatal/240 GDU) * Oral tablets of Alphintern® (Trypsin/Chymotrypsin 5 micro Katals/14 micro Katals) * Oral Tablets Non-Steroidal Anti-inflammatory drug (Cataflam® 50mg) Regarding the efficacy of the inferior alveolar nerve block anesthesia in mandibular molars with symptomatic irreversible pulpitis and post operative pain follow up for 3 days. The main question it aims to answer are: • Does premedication increase the success rate of inferior alveolar nerve block. Participants will describe their preoperative pain level to the investigator and describe their pain level during the treatment. Researchers will compare different premedication to see if it increases the success rate of inferior alveolar nerve block using Visual Analogue Scale (VAS), Electric Pulp testing and cavity test.