A Study to Assess Nicotine Uptake From a Menthol Electronic Nicotine Delivery System Product

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This will be a randomized, open-label, 2-way crossover, single-site study designed to evaluate elements of abuse liability (AL), including subjective effects and physiological measures (pharmacodynamics \[PD\]), and plasma nicotine uptake (pharmacokinetics \[PK\]) of Menthol ENDS investigational product (IP) relative to each participant\'s usual brand (UB) menthol cigarette. The study will be conducted in a confinement setting in generally healthy adult menthol cigarette smokers and dual users of menthol cigarettes and ENDS products.
Epistemonikos ID: 9037afa562fd7b7ae39f33faca93b300d665cd1d
First added on: Oct 21, 2026