Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Insomnia During the Withdrawal-Rehabilitation Period of Methamphetamine Use Disorder

The Department of Acupuncture-Moxibustion, the First Affiliated Hospital of Zhejiang Chinese Medical University is conducting a clinical research project entitled \"Randomized Controlled Clinical Trial of Transcutaneous Auricular Vagus Nerve Stimulation (transcutaneous auricular vagus nerve stimulation，taVNS) for Insomnia During the Withdrawal-Rehabilitation Period of Methamphetamine Use Disorder\". This study aims to explore the short-term clinical efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS), based on the theory of \"Heart-Kidney Interplay\", in improving insomnia among patients with methamphetamine use disorder in the withdrawal-rehabilitation period on the basis of routine drug-addiction rehabilitation. The primary efficacy outcome is the change in total score of the Insomnia Severity Index (Insomnia Severity Index,ISI) from baseline to Week 4. This project will commence in September 2026, and a total of 96 participants with methamphetamine use disorder in the withdrawal-rehabilitation period will be recruited.