Efficacy and Safety of Stapokibart in Non-Allergic Rhinitis With Eosinophilia Syndrome

Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The goal of this clinical trial is to learn if Stapokibart (CM310) works to treat Non-Allergic Rhinitis with Eosinophilia Syndrome (NARES) in adults. It will also learn about the safety of CM310. The main questions it aims to answer are: Does drug CM310 relieve the symptoms of participants? What medical problems do participants have when injecting CM310? Researchers will compare CM310 to a placebo (a look-alike substance that contains no drug) to see if CM310 works to treat NARES. Participants will: Inject CM310 or a placebo every 2 weeks for 12 weeks, and follow up for another 8 weeks. Visit the clinic once every 2 weeks for checkups and tests. Keep a diary of their symptoms every day.
Epistemonikos ID: 8fbbe76ce19b0e6581c073016df394ed3786910b
First added on: Nov 21, 2025