Systematic evaluation of the efficacy of acupuncture and western medicine in the treatment of Parkinson's disease

Objective: Systematic evaluation of the efficacy and safety of acupuncture and Western medicine in the treatment of Parkinson's disease. Method: Systematic retrieval of PubMed, Cochrane Library, CBM, CNKI, Wip, and all databases to incorporate randomized controlled trials of acupuncture and Western medicine in the treatment of Parkinson's disease. By Cochrane System Reviewer Manual 5.1 Quality evaluation, Meta analysis using RevMan5.3 software. Results: 1487 patients were included in the study in 21 randomized controlled trials. Meta analysis results show: ① Efficiency: Comparison of acupuncture and Western medicine is not statistically significant [RR=1.16,95% CI (0.99,1.35)], Acupuncture + Western medicine Drug comparison in No statistically significant difference on UPDRS reduction rate [RR=1.33,95% CI (0.99,1.78)], significant difference on Webster reduction rate [RR=1.25,95% CI (1.01,1.53)]; ② UPDRS score: Comparison of acupuncture vs. Western medicine No statistically significant [WMD=-2.55,95% CI (- 11.15,6.05)], there is a significant difference between acupuncture + Western medicine versus Western medicine [WMD=-0.43,95% CI (-0.70, -0.17)]; Webster score: Comparison of acupuncture vs. Western medicine is statistically significant [WMD=-2.5,95% CI (-2.77, -2.23)], acupuncture + Western medicine comparison Unisostat Significance [WMD=-6.48,95% CI (-20.19,7.22)]; ② Adverse reactions: 3 studies reported hallucinations, haloneedle, insomnia, dizziness, acceleration of heartbeat and other adverse reactions during acupuncture treatment. Conclusion: Upuncture may be an effective and safe treatment for Parkinson's disease.