Trazodone on OSA Endotypes

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2024
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for spontaneous upper airway (UA) dilator muscle recruitment. As a consequence they are exposed to apnea and hypopnea cycling. In this protocol the investigators will test the effect of trazodone administered before sleep on OSA traits and OSA severity during sleep.
Epistemonikos ID: 8eb9f95d1d59629127cbde0820ba1ad1c4d65ff7
First added on: May 15, 2024