A randomized, double-blind, placebo-controlled trial on the drug treatment on sleep bruxism

INTERVENTION: Clonazepam administration (1.0mg, 1‐day, before sleep) (Wash out 2 weeks) Clonidine administration (0.15mg, 1‐day, before sleep) (Wash out 2 weeks) Placebo administration (1‐day, before sleep) Clonazepam administration (1.0mg, 1‐day, before sleep) (Wash out 2 weeks) Placebo administration (1‐day, before sleep) (Wash out 2 weeks) Clonidine administration (0.15mg, 1‐day, before sleep) Clonidine administration (0.15mg, 1‐day, before sleep) (Wash out 2 weeks) Clonazepam administration (1.0mg, 1‐day, before sleep) (Wash out 2 weeks) Placebo administration (1‐day, before sleep) Clonidine administration (0.15mg, 1‐day, before sleep) (Wash out 2 weeks) Placebo administration (1‐day, before sleep) (Wash out 2 weeks) Clonazepam administration (1.0mg, 1‐day, before sleep) Placebo administration (1‐day, before sleep) (Wash out 2 weeks) Clonazepam administration (1.0mg, 1‐day, before sleep) (Wash out 2 weeks) Clonidine administration (0.15mg, 1‐day, before sleep) Placebo administration (1‐day, before sleep) (Wash out 2 weeks) Clonidine administration (0.15mg, 1‐day, before sleep) (Wash out 2 weeks) Clonazepam administration (1.0mg, 1‐day, before sleep) CONDITION: Sleep Bruxism PRIMARY OUTCOME: 1. Frequency of sleep bruxism episodes; 2. Masticatory muscle activity during sleep; 3. Frequency of tooth grinding noises SECONDARY OUTCOME: 1. Sleep‐stage distribution INCLUSION CRITERIA: Patient with sleep bruxism