Efficacy of an Adhesive Hydrocolloid Bandage on Wound Healing: findings of a 28-Day, Single-Centre, Randomised, Controlled Study

This single‐centre, randomised, controlled study assessed the wound healing efficacy of adhesive bandages in eligible healthy adults (N = 36) aged 25‐55 with Fitzpatrick skin types II and III using a model of laser‐induced wounds. Here, we report data for wounds that were randomised to treatment with either a hydrocolloid bandage for multi‐day use (BAND‐AID Adhesive Bandage Hydroseal), standard of care (SoC) (BAND‐AID Adhesive Bandage Tru‐Stay Sheer) or an uncovered control. Primary endpoints included the time to complete healing and a composite wound healing score. Hydrocolloid bandage‐treated wounds healed twice as fast as the uncovered control or SoC‐treated wounds. Median time (days) to complete healing was significantly faster for the hydrocolloid bandage‐treated wounds (6.9) versus SoC (11.9) and uncovered control (11.8). Hydrocolloid bandage‐treated wounds had significantly better composite wound healing scores versus SoC and versus uncovered control over 2 weeks. At Day 28, cosmesis was better with hydrocolloid bandage treatment (0.3) versus SoC (0.6) and uncovered control (2.1) (change from baseline in a composite scar score; higher score = worse outcome). Multi‐day wound occlusion with a hydrocolloid bandage promoted faster healing and improved cosmesis compared with daily SoC dressings or uncovered control.