A Study to Compare the effect of two different regimens of radiation and chemotherapy in patients of advanced cancer of the head and neck region who are deemed unfit for cure

INTERVENTION: Intervention1: Arm A‐Study arm: 42Gy/12 fractions/6 days a week with concurrent Cisplatin at a dose of 40 mg/m2 qweekly followed by assessment at 1 month post treatment for radical conversion if partial or complete response according to RECIST 1.1 Control Intervention1: Arm B ‐ Standard Arm: 20 Gy/5#/5 days with concurrent Cisplatin at a dose of 6 mg/m2 daily followed by assessment at 1 month post treatment for radical conversion if partial or complete response according to RECIST 1.1 CONDITION: Health Condition 1: C00‐C14‐ Malignant neoplasms of lip, oral cavity and pharyn X PRIMARY OUTCOME: Response RateTimepoint: 1 month and 3 months SECONDARY OUTCOME: Acute and Late toxicity assessmentTimepoint: Weekly/SOS during treatment Overall SurvivalTimepoint: 1 year Progression Free SurvivalTimepoint: 3 months and 6 months Quality of LifeTimepoint: Baseline, 3 months and 6 months INCLUSION CRITERIA: age‐18 to 70 years, biopsy proven locally advanced squamous cell carcinoma of head and neck except nasopharynx, PNS and salivary glands, deemed unfit for curative intent by head and neck multidisciplinary team, PS‐0‐2, no uncontrolled comorbidities, hb‐10, plt‐more than 100k, AST,ALT within three times ULN, bilirubin within ULN, viral markers negative, giving written informed consent