Application of thermosensitive hydroxybutyl chitosan hydrogel after third molar extraction

INTERVENTION: Participants were divided into experimental and control groups, the control group was given saline stored at the same temperature and the experimental group was given hydrogel. Randomization procedure: The two groups were preoperatively prepared using four sealed opaque envelopes; one pair to determine whether to use the hydrogel, and the other pair to determine whether to use the hydrogel on the left or right side. Before the operation, the patients were asked to extract an envelope from each of the two pairs, and the experimental group and the control group were determined according to the combined results. CONDITION: Impacted mandibular third molar extraction ; Oral Health PRIMARY OUTCOME: 1. Pain measured using the visual analogue scale (VAS) score on the first, third and seventh days after the operation; 2. Swelling: distance from the outer canthus to the mandibular angle (I), the tragus to the mouth angle (II) and the tragus to the mandibular angle (III) measured using a tape measure, and the following formula was applied: (I + II + III)/3 (mm) at baseline and the first, third and seventh days after the operation; 3. Mouth opening: distance between the tips of the upper and lower central incisors was measured using a Vernier calliper to evaluate the degree of mouth opening at baseline and the first, third and seventh days after the operation SECONDARY OUTCOME: 1. Quality of life measured using a questionnaire which included questions on social isolation, diet, sleep, appearance, and speech on the third and seventh days after the operation; 2. Wound healing: the inde Xreported was used to evaluate wound healing. The total score was 5 points, with higher scores indicating better healing, on the third and seventh days after the operation. INCLUSION CRITERIA: 1. Age 18‐35 years 2. American Society of Anaesthesiologists (ASA) status 1‐2 3. No seafood allergies 4. Pell, Gregory and Winter classification of class I, position B, and horizontal impaction, respectively 5. Good oral hygiene 6. No systemic diseases 7. Ability to cooperate in completing postoperative follow‐up