Efficacy of tolvaptan in transurethral resection of prostate

INTERVENTION: Intervention type:DRUG. Intervention1:Efficacy of tolvaptan in transurethral resection of prostate: A prospective randomized study, Dose form:TABLET, Route of administration:ORAL, intended dose regimen:3 group: control/7.5mg group/15mg group. CONDITION: Benign prostatic hypertrophy PRIMARY OUTCOME: Change of serum sodoum and occurrence of TUR syndrome. Timepoint:perioperative period. SECONDARY OUTCOME: 1) perioperative mortality; 2) neurological and circulatory abnormality; 3) serum creatinine levels; 4) lactate levels; . Timepoint: perioerative period. INCLUSION CRITERIA: 1) Benign prostatic hypertrophy 2) male: 20‐89 year‐old 3) patients showed consent of this study