Acetazolamide as a treatment after hemorrhagic stroke

INTERVENTION: In the intervention group, subjects will receive acetazolamide intravenously as well as treatment as usual. The dosage of acetazolamide will be similar to the average dosage used for the treatment of intracranial hypertension: 1.5 grams per day in three dosages of 0.5 grams in a 100 mL solution per dose. The intervention will be initiated within 72 hours after ictus, after aneurysm securing, and it will be continued until day 14 after ictus in addition to the usual treatment. The control group will not receive any study medication and will only receive treatment as usual. CONDITION: Aneurysm, Subarachnoid hemorrhage (SAH) ; ; PRIMARY OUTCOME: Cerebral perfusion (arterial spin labeling (ASL) MRI) on day 7±2 after ictus. SECONDARY OUTCOME: Cerebral perfusion (arterial spin labeling (ASL) MRI) on day 12±2 after ictus. ; ; Serious adverse events (SAEs) and serious unexpected serious adverse reactions (SUSARs) until 10 weeks after ictus. ; ; The occurrence of DCI. DCI will be defined as either “clinical deterioration or cerebral infarction due to delayed cerebral ischemia”. INCLUSION CRITERIA: =18 years old Aneurysm confirmed by the presence of subarachnoid blood by computed tomography (CT) or lumbar puncture and by visualization of the aneurysm on either CT angiography, MR angiography or digital subtraction angiography Hospital arrival =72 hours of ictus Eligible for aneurysm coiling