To compare the efficacy and safety of Herbavate vs. the conventional therapy in the management of Palmoplantar Keratoderma

INTERVENTION: Intervention1: Herbavate: To be applied on affected area 3 times a day for 4 weeks Control Intervention1: Topical Salicylic Acid (6% w/w): To be applied on affected area 3 times a day for 4 weeks CONDITION: Palmoplantar Keratoderma PRIMARY OUTCOME: Percentage reduction in area of involvement‐‐‐‐‐‐Timepoint: At the end of 2 and 4 weeks of treatment. SECONDARY OUTCOME: Global assessment by patients.( PaGA)‐‐‐‐‐‐Timepoint: End of Study (After 4 weeks) Improvement in symptoms‐‐‐‐‐‐Timepoint: At the end of 2 and 4 weeks of treatment. INCLUSION CRITERIA: 18 years of age or older. Clinical diagnosis of isolated (simple) palmoplantar keratoderma involving greter than or equal to 50 percent of the surface of involved acral areas. Be generally healthy as determined by brief medical history. Be capable of understanding and signing the consent form.