A multicenter randomized controlled study comparing needles with and without side hole for EUS guided fine needle biopsy in diagnosis of pancreatic solid lesions

INTERVENTION: EUS‐FNA needle with side hole EUS‐FNA needle without side hole CONDITION: Pancreatic tumors PRIMARY OUTCOME: Primary endpoints: Rate of satisfactory sampling for histological diagnosis, diagnositic accuracy.; Secondary endpoints: rate of adverse events, technical success rate INCLUSION CRITERIA: Pancreatic solid lesions depicted by imaging modalities ECOG performance status = 1, 2 No severe dysfunction in other organs Requirement of pathological diagnosis for patient treatment Written informed consent obtained from patients