A research of efficacy and safety of oxytocin administration to detect others altruism in children and adolescents with reactive attachment disorder

INTERVENTION: Intranasal single administration of oxytocin Intranasal single administration of placebo CONDITION: Reactive attachment disorder Autism‐spectrum disorder PRIMARY OUTCOME: Comparison of score of cognitive tasks change after oxytocin or placebo administration. SECONDARY OUTCOME: salivary oxytocin concentration ; oxytocin receptor gene polymorphism ; neuropsychological test INCLUSION CRITERIA: 1) Patients with reactive attachment disorder or autism spectrum disorder based on the classifications in the diagnostic and statistical manual of mental disorders (DSM‐5). Healthy children and adolescents with higher level of IQ 80. 2) Subjects within the age range of 10‐17 years old. 3) Must demonstrate an acceptable degree of compliance with medication and procedures in the opinion of the investigator.