A Clinical Trial of Aperiodic Tiling Microstructure Spectacle Lenses for Myopia Control in Children and Adolescents

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Multi‐point defocus lens group:Wear multi‐point defocus lenses;AMT group (aperiodic microstructure tiling group):Wear non‐periodic tessellated microstructure lenses for 12 months.;Single vision lens group:Wear single vision lenses; CONDITION: Myopia PRIMARY OUTCOME: Cycloplegic refraction; SECONDARY OUTCOME: Choroidal thickness;corrected visual acuity with spectacles;Visual function;Axial length; INCLUSION CRITERIA: 1.Age 8‐12 years at enrollment, of any gender; 2.Diagnosed with myopia, with cycloplegic objective computerized refractive spherical equivalent between ‐0.75D and ‐5.00D (inclusive of ‐0.75D and ‐5.00D); 3.Corrected visual acuity in each eye equal to or better than decimal visual acuity 1.0; 4.Willing to wear the trial lenses as required by the investigator (full‐time wear, not less than 10 hours per day), and complete scheduled visits as planned; 5.Able to understand and participate in the consent process, accompanied by a parent or guardian who can read and understand Chinese, and sign the informed consent/consent statement;
Epistemonikos ID: 8ae49394feb2f3a064c849751e9033945251a7fc
First added on: Oct 08, 2026