Preventive Effects of Bosentan on the Systemic Cardiovascular Consequence of Sleep Apnea

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2007
The study will compared the effects of bosentan, an endothelin receptor antagonist, and nasal continuous positive airway pressure (nCPAP), obstructive sleep apnea current reference treatment, on diastolic blood pressure in untreated mildly hypertensive sleep apnea patients. The hypothesis is that blocking endothelin receptors with a drug will have the same systemic blood pressure lowering effect than nCPAP in sleep apnea patients.
Epistemonikos ID: 8aa3a036517a3ef1d3ee434eff505c1b0f5fcb6f
First added on: May 05, 2024