Prophylaxis of Psychiatric Symptoms During Anti-HCV Treatment

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2005
The treatment of chronic hepatitis C with peginterferon and ribavirin is highly effective but is hampered by peginterferon-induced psychopathology. Prevention of peginterferon-induced psychopathology with selective serotonin reuptake inhibitors (SSRI\'s) (paroxetine) has been shown to be effective in patients treated with interferon for malignant disease. The aim is to study the effects of prophylactic treatment with escitalopram (another SSRI) on peginterferon-associated psychopathology in patients treated with peginterferon and ribavirin for chronic hepatitis C.
Epistemonikos ID: 894e0442632241a42bc9272ba6284ffaefedc8d2
First added on: May 04, 2024