A randomized trial of low-dose rectal diclofenac for prevention of post endoscopic retrograde cholangiopancreatography pancreatitis

INTERVENTION: Diclofenac group is administered with 50 mg of rectal diclofenac 30 min before ERCP with saline infusion (for patients weighing less than 50 kg, the dose of diclofenac was reduced to 25 mg). Control group is administered with saline infusion only. CONDITION: Post‐ERCP pancreatitis PRIMARY OUTCOME: The occurrence of PEP as defined by the criteria of Cotton as the development of abdominal pain and elevation of serum amylase level greater than three times the upper normal limit within 24 hours after ERCP INCLUSION CRITERIA: Patients who are planned ERCP.