Comparison of the effect of aromatherapy and edible rose essential oil on saliva cortisol level and quality of life of chronic renal failure patients undergoing hemodialysis

INTERVENTION: Intervention 1: Intervention group number 1 (aroma therapy): When the patient is connected to the dialysis machine, a piece of cloth soaked in 3 drops of rose essence with a concentration of 2% is attached to the patient's neck and the patient will be asked to breathe normally. This work will be done 3 times a day and each time for 5 minutes for 4 weeks. Intervention 2: Intervention group number 2 (oral intake): When the patient is connected to the dialysis machine, 15 drops of rose extract will be poured into some water every 8 hours and given to him/her. Totally, 3 doses of medicine will be given to the patient daily. CONDITION: N18.5 Patients with chronic renal failure under hemodialysis. ; Chronic kidney disease, stage 5 PRIMARY OUTCOME: Quality of life. Timepoint: Quality of life at the beginning of the study (before the intervention) and one month later. Method of measurement: Kidney Disease Quality of Life‐Short Form (KDQOL‐SF) questionnaire. Salivary cortisol levels. Timepoint: Salivary cortisol levels at the beginning of the study (before the intervention) and one month later. Method of measurement: By ELISA kits. INCLUSION CRITERIA: Ability to communicate and answer questions Consent to participate in the study and sign the informed consent form Healthy sense of smell Not having an anxiety disorders Not having a history of using aromatherapy Not having asthma and allergies Not brushing teeth At least three months have passed since hemodialysis Doing dialysis at least 2 to 3 times a week Not taking corticosteroids and immunosuppressants Not having active infection Not having a history of organ transplant rejection Dialysis in the morning shift No history of cancer