Comparison of three sedative agents; intranasal dexmedetomidine, intranasal midazolam and inhalation nitrous oxide for children undergoing dental treatment

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2022
INTERVENTION: Intervention1: Intranasal midazolam: Given using an intranasal atomization device at a dose of 0.3 mg/kg Intervention2: Intranasal dexmedetomidine, Intranasal Midazolam: Given using an intranasal atomization device at a dose of 1 µg/kg, given using intranasal atomization device at a dose of 0.3 mg/kg Control Intervention1: Nitrous oxide‐Oxygen: Inhalation nitrous‐oxide oxygen is the gold standard. Maximum titration is 70% Oxygen and 30% Nitrous oxide CONDITION: Health Condition 1: K029‐ Dental caries, unspecified PRIMARY OUTCOME: Assessment of sedation and behaviour ; Intra‐ and Post‐op painTimepoint: Assessment of sedation and behaviour ; Intra‐ and Post‐op pain SECONDARY OUTCOME: Physiologic signs (Blood pressure, SPO2, Pulse rate) ; Recovery time ; Side effectsTimepoint: During administration of local anaesthesia, during insertion of mouth prop, during obturation ; Post treatment INCLUSION CRITERIA: 1.ASA I Category 2.Behavior category: Frankl Scale 2 negative 3.Requiring pulpectomy in at least three posterior teeth in the lower arch 4.No cognitive impairment
Epistemonikos ID: 88a84992c3f5a0a91a1280da29a1b44f8f2fc345
First added on: Aug 01, 2024