Randomized controlled clinical study on the effect of early oral rivaroxaban on the prognosis of patients with acute ST-segment elevation myocardial infarction undergoing emergency PCI

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2023
INTERVENTION: Rivaroxaban group:Rivaroxaban (5 mg St / 10 mg st) + aspirin 300 mg + clopidogrel bisulfate 300 mg or ticagrelor 180 mg;placebo group:Placebo + aspirin 300mg + clopidogrel bisulfate 300mg or ticagrelor 180mg; CONDITION: Acute PRIMARY OUTCOME: major adverse cardiac events; SECONDARY OUTCOME: Cardiac related rehospitalization and all‐cause death; INCLUSION CRITERIA: (1) Age = 18 (2) For the first STEMI, the diagnostic criteria are in accordance with the Guidelines for the Diagnosis and Treatment of Acute ST‐segment Elevation Myocardial Infarction, and the following points must be met: ? Ischemic post‐sternal pain attack lasts for more than 20‐30 minutes; ? ECG has two or more adjacent leads with ST segment elevation (limb lead>0.1mv, precordial lead>0.2mv) or new left bundle branch block; ? With or without serum markers, at least 99% of the reference value; ? See a doctor within 12 hours after the onset of STEMI.
Epistemonikos ID: 88953adaaa41512e0ac3d7535ff5fb1bdacce2b4
First added on: Feb 20, 2024