TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2021
Unmethylated cystine-guanosine dinucleotide (CpG) motifs are pathogen-associated molecular patterns (PAMPs) associated with bacterial and viral-derived DNA that activate the innate and humoral immunity via toll-like receptor 9. This is a randomized controlled pilot study evaluating the clinical and immune correlates of a seroprotective immune response against a CpG-adjuvanted vaccine for hepatitis B.
Epistemonikos ID: 885e6bbc2cfe562744eab87adb41a590f648b03b
First added on: Nov 24, 2021