To explore the mechanism of acupuncture intervention on insulin resistance of phlegm-dampness polycystic ovary syndrome based on oxidative homeostasis

INTERVENTION: The metformin group:Start oral letrozole on the 3rd day of menstruation, 2.5 mg/day, continuously for 5 days. Instruct the patient to undergo dynamic monitoring of follicle development by ultrasound on the 11th day of menstruation. When the follicle diameter is =15mm, monitor every other day; if =15mm, monitor daily until the follicle diameter is =18mm, defined as mature follicle. Administer 10,000 units of human chorionic gonadotropin (HCG) intramuscularly to induce follicle rupture post‐ovulation, followed by guidance on intercourse. After ovulation, take oral dydrogesterone tablets, 10mg per dose, twice daily, for 14 consecutive days. Additionally, add oral metformin to the above basic medication regimen, taken with meals, 500mg per dose, twice daily, continuously for 3 menstrual cycles.;Acupuncture group:Start taking oral letrozole on the 3rd day of menstruation, 2.5 mg/day, for 5 consecutive days. Instruct the patient to undergo dynamic monitoring of follicle development by transvaginal ultrasound starting on the 11th day of menstruation. When the follicle diameter is =15mm, monitor every other day; if =15mm, monitor daily until the follicle diameter is =18mm, defined as a mature follicle. Administer 10000 units of human chorionic gonadotropin (HCG) by intramuscular injection to induce follicle rupture and advise intercourse. After ovulation, take oral dydrogesterone tablets, 10mg per dose, twice daily for 14 consecutive days. In addition to the basic medication treatment, acupuncture using Jiajian brand acupuncture needles with a size of 0.30×40mm is applied. Acupuncture method: needle insertion depth of approximately 0.8 1.5 inches, based on Deqi sensation. Acupoints selected include Neiguan (both sides), Guanyuan, Qihai, Zhongwan, Sanyinjiao (both sides), Fenglo CONDITION: Polycystic Ovary Syndrome PRIMARY OUTCOME: Six sex hormones;Anti‐Müllerian Hormone;Blood Sugar;Oral glucose tolerance test;Insulin Release Test;Interleukin‐6;Record pregnancy status.; SECONDARY OUTCOME: Cholesterol;Triglyceride;Low‐density lipoprotein‐C;Lipoprotein(a);High‐density lipoprotein‐C;Reactive Oxygen Species;Malondialdehyde;Nitric oxide;Total Antioxidant Status;Superoxide Dismutase;Glutathione peroxidase;Interleukin‐2;Interleukin‐10;Tumor Necrosis Factor‐a;Traditional Chinese Medicine Symptom Score;Ovarian follicle development;Endometrial thickness on ovulation day;Blood flow in the uterine cavity; INCLUSION CRITERIA: 1.Patients who meet the diagnostic criteria of Chinese and Western medicine; 2.Patients between the ages of 20 and 40 who have fertility requirements; 3.Patients with insulin resistance; 4.Those who voluntarily join and can perform regular visits.