A randomised trial for the treatment of AL amyloidosis with the high dose Green Tea Extract

INTERVENTION: standerd therapy plus the high dose green tea therapy. Drug: green tea extract powder Pharmaceutical formulation: capsules dose 2400 mg/d p.o. for 6 months every day standerd therapy CONDITION: ligh chain amyloidosis PRIMARY OUTCOME: compare the 3 and 6 month change in each organ involvement such as cardiac troponin T, NT‐proBNP, interventricular septum thickness, ejection fraction, quantitative immunoglobulins, serum beta2 microglobulin, serum‐free light chains, urinary albumin, derivatives of reactive oxygen metabolites, and biochemical antioxidant potential. INCLUSION CRITERIA: 1. Biopsy proven systemic AL amyloidosis. 2. At least one evaluable organ involvement. 3. Ability of subject to understand character and individual consequences of the clinical trail. 4. Written informed consent. 5. Ability of subject to intake capsules.