effects of propranolol and levetiracetam to prevent migraine attacks in children 5-15 year-old children

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: Intervention 1: Intervention group: In the intervention group, the Levetirastam tablet with brand name of Levebel made by Koobl Daroo Co. at a daily dose of 20 mg/kg is prescribed for 3 months. Intervention 2: Control group: In control group, 0.5‐1 mg/kg Propranol tablet made by Koobl Daroo Co. is prescribed in two divided doses for 3 months. CONDITION: Migraine. ; Migraine PRIMARY OUTCOME: Headache duration. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: minute. Headache severity. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: Visual Analogue Scales (From a score of 1‐10 that is scored by the child). SECONDARY OUTCOME: Number of migraine attacks per month. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: Number in the questionnaire. Severity of disability due to headache. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: Questionnaire (Grade 1: Score 0‐10, Grade 2: Score 11‐30, Grade 3: Score 31‐50 and Grade 4: Scores above 50). Side effects of medication (Dizziness, drowsiness, weight loss, anorexia, memory impairment, imbalance, skin complications). Timepoint: The 3rd month and 6th month. Method of measurement: Questionnaire. INCLUSION CRITERIA: Age 5 to 15 years migraine attacks headache more than once a week Headache causing a child's disability (PedMIDAS score more than 20) Headache prophylaxis is required in the child
Epistemonikos ID: 84bbcd76607cd7c05712b00336a9c94e105566d8
First added on: Apr 22, 2021